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1

Structure of the yellow fever NS5 protein reveals conserved drug targets shared among flaviviruses

Dubankova, Anna, Boura, Evzen

Journal:

Antiviral Research

Year:

2019

File:

PDF, 27.87 MB

2019

2

High-Throughput Screening and Quantum Mechanics for Identifying Potent Inhibitors against Mac1 Domain of SARS-CoV-2 Nsp3

Selvaraj, Chandrabose, Dinesh, Dhurvas Chandrasekaran, Panwar, Umesh, Boura, Evzen, Singh, Sanjeev Kumar

Journal:

IEEE/ACM Transactions on Computational Biology and Bioinformatics

Year:

2020

File:

PDF, 1.10 MB

2020

3

Minor capsid proteins of mouse polyomavirus are inducers of apoptosis when produced individually but are only moderate contributors to cell death during the late phase of viral infection

Sandra Huerfano, Vojtěch Žíla, Evžen Bouřa, Hana Španielová, Jitka Štokrová, Jitka Forstová

Journal:

Year:

2010

Language:

english

File:

PDF, 1.14 MB

english, 2010

4

Solution Structure of the ESCRT-I and -II Supercomplex: Implications for Membrane Budding and Scission

Evzen Boura, Bartosz Różycki, Hoi Sung Chung, Dawn Z. Herrick, Bertram Canagarajah, David S. Cafiso, William A. Eaton, Gerhard Hummer, James H. Hurley

Journal:

Year:

2012

Language:

english

File:

PDF, 1.51 MB

english, 2012

5

Membrane Budding

James H. Hurley, Evzen Boura, Lars-Anders Carlson, Bartosz Różycki

Journal:

Year:

2010

Language:

english

File:

PDF, 1.31 MB

english, 2010

6

Structure and Function of the ESCRT-II-III Interface in Multivesicular Body Biogenesis

Young Jun Im, Thomas Wollert, Evzen Boura, James H. Hurley

Journal:

Developmental Cell

Year:

2009

Language:

english

File:

PDF, 1.38 MB

english, 2009

7

14-3-3 protein interacts with and affects the structure of RGS domain of regulator of G protein signaling 3 (RGS3)

Lenka Rezabkova, Evzen Boura, Petr Herman, Jaroslav Vecer, Lenka Bourova, Miroslav Sulc, Petr Svoboda, Veronika Obsilova, Tomas Obsil

Journal:

Journal of Structural Biology

Year:

2010

Language:

english

File:

PDF, 595 KB

english, 2010

8

Two-Site Recognition of Phosphatidylinositol 3-Phosphate by PROPPINs in Autophagy

Baskaran, Sulochanadevi, Ragusa, Michael J., Boura, Evzen, Hurley, James H.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.88 MB

english, 2012

9

Using cryoEM Reconstruction and Phase Extension to Determine Crystal Structure of Bacteriophage ϕ6 Major Capsid Protein

Nemecek, Daniel, Plevka, Pavel, Boura, Evzen

Journal:

The Protein Journal

Year:

2013

Language:

english

File:

PDF, 518 KB

english, 2013

10

Subunit Folds and Maturation Pathway of a dsRNA Virus Capsid

Nemecek, Daniel, Boura, Evzen, Wu, Weimin, Cheng, Naiqian, Plevka, Pavel, Qiao, Jian, Mindich, Leonard, Heymann, J. Bernard, Hurley, James H., Steven, Alasdair C.

Journal:

Year:

2013

Language:

english

File:

PDF, 4.00 MB

english, 2013

11

14-3-3 Protein Interacts with Nuclear Localization Sequence of Forkhead Transcription Factor FoxO4

Obsilova, Veronika, Vecer, Jaroslav, Herman, Petr, Pabianova, Anna, Sulc, Miroslav, Teisinger, Jan, Boura, Evzen, Obsil, Tomas

Journal:

Year:

2005

Language:

english

File:

PDF, 272 KB

english, 2005

12

The 14-3-3 Protein Affects the Conformation of the Regulatory Domain of Human Tyrosine Hydroxylase †

Obsilova, Veronika, Nedbalkova, Eliska, Silhan, Jan, Boura, Evzen, Herman, Petr, Vecer, Jaroslav, Sulc, Miroslav, Teisinger, Jan, Dyda, Fred, Obsil, Tomas

Journal:

Year:

2008

Language:

english

File:

PDF, 303 KB

english, 2008

13

Large, dynamic, multi-protein complexes: a challenge for structural biology

Różycki, Bartosz, Boura, Evzen

Journal:

Journal of Physics Condensed Matter

Year:

2014

Language:

english

File:

PDF, 630 KB

english, 2014

14

Structural basis for iron piracy by pathogenic Neisseria

Noinaj, Nicholas, Easley, Nicole C., Oke, Muse, Mizuno, Naoko, Gumbart, James, Boura, Evzen, Steere, Ashley N., Zak, Olga, Aisen, Philip, Tajkhorshid, Emad, Evans, Robert W., Gorringe, Andrew R., Maso

Journal:

Year:

2012

Language:

english

File:

PDF, 1.66 MB

english, 2012

15

Membrane-Elasticity Model of Coatless Vesicle Budding Induced by ESCRT Complexes

Różycki, Bartosz, Boura, Evzen, Hurley, James H., Hummer, Gerhard, Pande, Vijay S.

Journal:

PLoS Computational Biology

Year:

2012

Language:

english

File:

PDF, 414 KB

english, 2012

16

Phosphatidylinositol 4-kinases: Function, structure, and inhibition

Boura, Evzen, Nencka, Radim

Journal:

Experimental Cell Research

Year:

2015

Language:

english

File:

PDF, 1.87 MB

english, 2015

17

The high-resolution crystal structure of phosphatidylinositol 4-kinase IIβ and the crystal structure of phosphatidylinositol 4-kinase IIα containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design

Klima, Martin, Baumlova, Adriana, Chalupska, Dominika, Hřebabecký, Hubert, Dejmek, Milan, Nencka, Radim, Boura, Evzen

Journal:

Acta Crystallographica Section D Biological Crystallography

Year:

2015

Language:

english

File:

PDF, 2.04 MB

english, 2015

18

Solution structure of the ESCRT-I complex by small-angle X-ray scattering, EPR, and FRET spectroscopy

Evzen Boura, Bartosz Różycki, Dawn Z. Herrick, Hoi Sung Chung, Jaroslav Vecer, William A. Eaton, David S. Cafiso, Gerhard Hummer and James H. Hurley

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.59 MB

english, 2011

19

Corrigendum to: ‘‘Phosphatidylinositol 4-kinases: Function, structure, and inhibition’’ [Exp. Cell Res. 337/2 (2015) 136–145]

Boura, Evzen, Nencka, Radim

Journal:

Experimental Cell Research

Year:

2016

File:

PDF, 135 KB

2016

20

Adenosine triphosphate analogs can efficiently inhibit the Zika virus RNA-dependent RNA polymerase

Hercík, Kamil, Kozak, Jaroslav, Šála, Michal, Dejmek, Milan, Hřebabecký, Hubert, Zborníková, Eva, Smola, Miroslav, Ruzek, Daniel, Nencka, Radim, Boura, Evzen

Journal:

Antiviral Research

Year:

2017

Language:

english

File:

PDF, 1.44 MB

english, 2017

21

Fluorescent Inhibitors as Tools To Characterize Enzymes: Case Study of the Lipid Kinase Phosphatidylinositol 4-Kinase IIIβ (PI4KB)

Humpolickova, Jana, Mejdrová, Ivana, Matousova, Marika, Nencka, Radim, Boura, Evzen

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.40 MB

english, 2017

22

Kobuviral Non-structural 3A Proteins Act as Molecular Harnesses to Hijack the Host ACBD3 Protein

Klima, Martin, Chalupska, Dominika, Różycki, Bartosz, Humpolickova, Jana, Rezabkova, Lenka, Silhan, Jan, Baumlova, Adriana, Dubankova, Anna, Boura, Evzen

Journal:

Year:

2017

Language:

english

File:

PDF, 4.63 MB

english, 2017

23

Crystal structures of a yeast 14-3-3 protein from Lachancea thermotolerans in the unliganded form and bound to a human lipid kinase PI4KB-derived peptide reveal high evolutionary conservation

Eisenreichova, Andrea, Klima, Martin, Boura, Evzen

Journal:

Acta Crystallographica Section F Structural Biology Communications

Year:

2016

Language:

english

File:

PDF, 1.57 MB

english, 2016

24

Metal ions-binding T4 lysozyme as an intramolecular protein purification tag compatible with X-ray crystallography

Boura, Evzen, Baumlova, Adriana, Chalupska, Dominika, Dubankova, Anna, Klima, Martin

Journal:

Protein Science

Year:

2017

Language:

english

File:

PDF, 998 KB

english, 2017

25

Structural basis of Zika virus methyltransferase inhibition by sinefungin

Hercik, Kamil, Brynda, Jiri, Nencka, Radim, Boura, Evzen

Journal:

Archives of Virology

Year:

2017

Language:

english

File:

PDF, 2.17 MB

english, 2017

26

Structural analysis of phosphatidylinositol 4-kinase IIIβ (PI4KB) – 14-3-3 protein complex reveals internal flexibility and explains 14-3-3 mediated protection from degradation in vitro

Chalupska, Dominika, Eisenreichova, Andrea, Różycki, Bartosz, Rezabkova, Lenka, Humpolickova, Jana, Klima, Martin, Boura, Evzen

Journal:

Journal of Structural Biology

Year:

2017

Language:

english

File:

PDF, 981 KB

english, 2017

27

Negative charge and membrane-tethered viral 3B cooperate to recruit viral RNA dependent RNA polymerase 3D pol

Dubankova, Anna, Humpolickova, Jana, Klima, Martin, Boura, Evzen

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 4.57 MB

english, 2017

28

PI(4,5)P 2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER–PM contact sites

Sohn, Mira, Korzeniowski, Marek, Zewe, James P., Wills, Rachel C., Hammond, Gerald R.V., Humpolickova, Jana, Vrzal, Lukas, Chalupska, Dominika, Veverka, Vaclav, Fairn, Gregory D., Boura, Evzen, Balla,

Journal:

The Journal of Cell Biology

Year:

2018

Language:

english

File:

PDF, 2.90 MB

english, 2018

29

The structural model of Zika virus RNA-dependent RNA polymerase in complex with RNA for rational design of novel nucleotide inhibitors

Šebera, Jakub, Dubankova, Anna, Sychrovský, Vladimír, Ruzek, Daniel, Boura, Evzen, Nencka, Radim

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 4.39 MB

english, 2018

30

Structural basis for recognition and repair of the 3′-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis

Silhan, Jan, Zhao, Qiyuan, Boura, Evzen, Thomson, Hellen, Förster, Andreas, Tang, Christoph M, Freemont, Paul S, Baldwin, Geoff S

Journal:

Nucleic Acids Research

Year:

2018

Language:

english

File:

PDF, 3.29 MB

english, 2018

31

Phosphatidylinositol 4-kinase IIIβ (PI4KB) forms highly flexible heterocomplexes that include ACBD3, 14-3-3, and Rab11 proteins

Chalupska, Dominika, Różycki, Bartosz, Humpolickova, Jana, Faltova, Lenka, Klima, Martin, Boura, Evzen

Journal:

Scientific Reports

Year:

2019

File:

PDF, 2.18 MB

2019

32

Convergent evolution in the mechanisms of ACBD3 recruitment to picornavirus replication sites

Horova, Vladimira, Lyoo, Heyrhyoung, Różycki, Bartosz, Chalupska, Dominika, Smola, Miroslav, Humpolickova, Jana, Strating, Jeroen R. P. M., van Kuppeveld, Frank J. M., Boura, Evzen, Klima, Martin, Bel

Journal:

Year:

2019

Language:

english

File:

PDF, 9.25 MB

english, 2019

33

No magnesium is needed for binding of the stimulator of interferon genes to cyclic dinucleotides

Smola, Miroslav, Birkus, Gabriel, Boura, Evzen

Journal:

Acta Crystallographica Section F Structural Biology Communications

Year:

2019

Language:

english

File:

PDF, 1005 KB

english, 2019

34

A large scale high-throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha

Sengupta, Nivedita, Jović, Marko, Barnaeva, Elena, Kim, David W., Hu, Xin, Southall, Noel, Dejmek, Milan, Mejdrova, Ivana, Nencka, Radim, Baumlova, Adriana, Chalupska, Dominika, Boura, Evzen, Ferrer,

Journal:

The Journal of Lipid Research

Year:

2019

File:

PDF, 4.75 MB

2019

35

Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19

Selvaraj, Chandrabose, Dinesh, Dhurvas Chandrasekaran, Panwar, Umesh, Abhirami, Rajaram, Boura, Evzen, Singh, Sanjeev Kumar

Journal:

Journal of Biomolecular Structure and Dynamics

Year:

2020

File:

PDF, 3.84 MB

2020

36

Structural analysis of the putative SARS-CoV-2 primase complex

Konkolova, Eva, Klima, Martin, Nencka, Radim, Boura, Evzen

Journal:

Journal of Structural Biology

Year:

2020

File:

PDF, 2.27 MB

2020

37

Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin

Krafcikova, Petra, Silhan, Jan, Nencka, Radim, Boura, Evzen

Journal:

Nature Communications

Year:

2020

File:

PDF, 2.24 MB

2020

38

Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses

Konkolova, Eva, Dejmek, Milan, HÅebabeckÃ½, Hubert, Å Ã¡la, Michal, BÃ¶serle, JiÅÃ, Nencka, Radim, Boura, Evzen

Journal:

Antiviral Research

Year:

2020

File:

PDF, 1.86 MB

2020

39

Defining the subcellular distribution and metabolic channeling of phosphatidylinositol

Pemberton, Joshua G., Kim, Yeun Ju, Humpolickova, Jana, Eisenreichova, Andrea, Sengupta, Nivedita, Toth, Daniel J., Boura, Evzen, Balla, Tamas

Journal:

The Journal of Cell Biology

Year:

2020

File:

PDF, 11.04 MB

2020